Design, synthesis, biological evaluation and molecular modeling investigation of new N'-(2-Thiouracil-5-oyl) hydrazone derivatives as potential anti-breast cancer and …
AAS El-Etrawy, FF Sherbiny - Journal of Molecular Structure, 2021 - Elsevier
… hydrazones as versatile precursors combined with thiouracil derivatives for the synthesis of
a variety of biologically … target for anticancer agents, due to its pivotal role in DNA synthesis; …
a variety of biologically … target for anticancer agents, due to its pivotal role in DNA synthesis; …
Synthesis and Biological Evaluation of Some Novel Bis-Thiadiazoles as Antimicrobial and Antitumor Agents
WAMA El-Enany, SM Gomha, W Hussein… - Polycyclic Aromatic …, 2021 - Taylor & Francis
… 2CH 3 , 4Ar-H, and 2 hydrazide NH and 2 hydrazone NH, respectively, in addition to the 10
Ar-H. … Newly synthesized target compounds were also evaluated for their in vitro antifungal …
Ar-H. … Newly synthesized target compounds were also evaluated for their in vitro antifungal …
[HTML][HTML] Synthesis, Characterization, and Biological Evaluation of Some Novel Pyrazolo[5,1-b]thiazole Derivatives as Potential Antimicrobial and Anticancer Agents
… the appropriate aromatic aldehyde to afford the corresponding hydrazones 3a,b (Scheme 1).
… All tested compounds except compound 8 showed high antifungal activity against Candida …
… All tested compounds except compound 8 showed high antifungal activity against Candida …
Anticancer, antimicrobial activities of quinoline based hydrazone analogues: Synthesis, characterization and molecular docking
… anticancer agents bendamustine and chlorambucil, revealed that the quinolyl hydrazones
holds promise as a potential anticancer agents. … as well as antifungal activity with MIC value …
holds promise as a potential anticancer agents. … as well as antifungal activity with MIC value …
Synthesis, structural characterization, and biological evaluation of some hydrazone compounds as potential antioxidant agents
… While the hydrazone compounds (II–VIII) synthesized in this study are used for different …
evaluated before. There have been many studies in the literature on antibacterial, antifungal, …
evaluated before. There have been many studies in the literature on antibacterial, antifungal, …
Synthesis, anticancer and antimicrobial evaluation of new pyridyl and thiazolyl clubbed hydrazone scaffolds
… and antifungal … new pyridyl and thiazolyl clubbed hydrazone scaffolds starting from an
antitubercular drug, prothionamide. The synthesized hydrazone derivatives were evaluated for …
antitubercular drug, prothionamide. The synthesized hydrazone derivatives were evaluated for …
New piperazine-hydrazone derivatives as potential antimicrobial agents: Synthesis, characterization, biological evaluation, and in silico investigations
… , the synthesis and biological activity of a new series of piperazine-hydrazone derivatives
have … , compounds were synthesized based on antimicrobial and antifungal compounds. The …
have … , compounds were synthesized based on antimicrobial and antifungal compounds. The …
[HTML][HTML] Synthesis and biological evaluation of some novel thiazole-based heterocycles as potential anticancer and antimicrobial agents
… The development of new antitumor agents represents an … Treatment of hydrazone derivative
3 with the appropriate … On the contrary, all synthesized compounds had no antifungal activity …
3 with the appropriate … On the contrary, all synthesized compounds had no antifungal activity …
Design, synthesis, anti-proliferative, anti-microbial, anti-angiogenic activity and in silico analysis of novel hydrazone derivatives
… anticandidal derivatives than standard antifungal antibiotics. The QSAR analysis suggested
that the tumor specificity of the hydrazone … SC Synthesis and biological evaluation of Schiff’s …
that the tumor specificity of the hydrazone … SC Synthesis and biological evaluation of Schiff’s …
[HTML][HTML] Synthesis and biological evaluation of thiazolyl-ethylidene hydrazino-thiazole derivatives: a novel heterocyclic system
LA Al-Mutabagani, FM Abdelrazek, SM Gomha… - Applied Sciences, 2021 - mdpi.com
… identifying new lead compounds, notably anticancer drugs [19,… appearance in several clinically
available anticancer drugs, … variable in vitro antibacterial and antifungal activities (Table 1…
available anticancer drugs, … variable in vitro antibacterial and antifungal activities (Table 1…